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Macrophages, Langerhans Cells, Interdigitating and Dendritic Accessory Cells: A Summary

  • Elisabeth C. M. Hoefsmit
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Abstract

Adherent or accessory cells, previously indicated as “A”-cells are of paramount importance in the immune response in vitro as well as in vivo. The nonlymphoid adherent population of peritoneal exudate cells, which have phagocytic properties, comprise the accessory cells which have to be present in lymphoproliferative responses in vitro. Most of these cells were obviously macrophages. However, they constitute a heterogeneous population of cells. It appeared that only a minority (8–15%) of these cells bear the Ia determinants of the immune response gene complex (1) which determines their antigen presenting function. Moreover, macrophages may change their properties in this respect during adhesion in vitro (2).

Keywords

Accessory Cell Mononuclear Phagocyte System Antigen Present Function Peripheral Lymphoid Organ Birbeck Granule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    R.H. Schwartz, H.B. Dickler, H.D. Sachs, and B.D. Schwartz. Scand. J. Immunol. 5:731 (1976).PubMedCrossRefGoogle Scholar
  2. 2.
    C. Cowing, B.D. Schwartz, and H.B. Dickler. J. Immunol. 120:378 (1978).PubMedGoogle Scholar
  3. 3.
    E.C.M. Hoefsmit, _in: “Mononuclear phagocytes in immunity, infection and pathology,” p. 129, R. van Fürth, ed., Blackwell, Oxford (1975).Google Scholar
  4. 4.
    E.C.M. Hoefsmit, E.W.A. Kamperdijk, and B.M. Balfour, in: “Mononuclear phagocytes, functional aspects,” vol. 2, p. 1809, R. van Fürth, ed., Martinus Nijhoff, The Hague (1980).Google Scholar
  5. 5.
    I. Silberberg, R.L. Baer, S.A. Rosenthal, G.J. Thorbecke and V. Berezowsky. Clin. Res. 23:231A (1975).Google Scholar
  6. 6.
    R.M. Steinman, and Z.A. Cohn. J. Exp. Med. 137:1142 (1973).PubMedCrossRefGoogle Scholar
  7. 7.
    R.M. Steinman, and M.C. Nussenzweig. Immunol. Rev. 53:127 (1980).PubMedCrossRefGoogle Scholar
  8. 8.
    G.J.V. Nossal, A. Abbot, J. Mitchell, and Z. Lummus. J. Exp. Med. 127:277 (1968).PubMedCrossRefGoogle Scholar
  9. 9.
    E.C.M. Hoefsmit, E.W.A. Kamperdijk, H.R. Hendriks, R.H.J. Beelen, and B.M. Balfour, in: “The reticuloendothelial system: a comprehensive treatise,” vol. I Morphology, p. 417, I. Carr, and W.T. Daems, eds., Plenum Publishing Corporation, New York (1980).Google Scholar
  10. 10.
    H.L. Langevoort, Z.A. Cohn, J.G. Hirsch, J.H. Humphrey, W.G. Spector, and R. van Fürth, in: “Mononuclear phagocytes,” p. 1, R. van Furth, ed., Blackwell, Oxford (1970).Google Scholar
  11. 11.
    Z.A. Cohn, and E. Wiener. J. Exp. Med. 118:991 (1963).PubMedCrossRefGoogle Scholar
  12. 12.
    S.G. Rice, and M. Fischman. Cell. Immunol. 11:130 (1974).PubMedCrossRefGoogle Scholar
  13. 13.
    W.S. Walker. Nature New Biology 229:211 (1971).PubMedGoogle Scholar
  14. 14.
    W.S. Walker. Immunology 26:1025 (1974).PubMedGoogle Scholar
  15. 15.
    K.-C. Lee, A. Wilkinson, and M. Wong. Cell. Immunol. 48:79 (1979).PubMedCrossRefGoogle Scholar
  16. 16.
    E. Tzehoval, R. de Baetselier, M. Feldman, and S. Segal. Eur. J. Immunol. 11:323 (1981).PubMedCrossRefGoogle Scholar
  17. 17.
    R.V. Blanden, M.J. Lefford, and G.B. Mackaness. J. Exp. Med. 129:1079 (1969).PubMedCrossRefGoogle Scholar
  18. 18.
    D.J. Beller, J.M. Kiely, and E.R. Unaue. J. Immunol. 124: 1426 (1980).PubMedGoogle Scholar
  19. 19.
    J.B. Toews, P.R. Bergstresser, and J. Wayne Streilein. J. Invest. Dermatol. 75:78 (1980).PubMedCrossRefGoogle Scholar
  20. 20.
    I. Silberberg-Sinakin, and G.J. Thorbecke. J. Invest. Dermatol. 75:61 (1980).PubMedCrossRefGoogle Scholar
  21. 21.
    H. Ebner, and G. Niebauer. Arch. Klin. U. Exp. Derm. 229:217 (1967).CrossRefGoogle Scholar
  22. 22.
    G. Stingl, K. Tamaki, and S.I. Katz. Immunol. Rev. 53:149 (1980).PubMedCrossRefGoogle Scholar
  23. 23.
    R.H. Kelly, B.M. Balfour, J.A. Armstrong, and S. Griffiths. Anat. Rec. 190:5 (1978).PubMedCrossRefGoogle Scholar
  24. 24.
    E.W.A. Kamperdijk, E.M. Raaymakers, J.H.S. de Leeuw, and E.C.M. Hoefsmit. Cell Tiss. Res. 192:1 (1978).CrossRefGoogle Scholar
  25. 25.
    W.H. Gerneke. J. South Afr. Veterin. Assoc. 51/3:137 (1980).Google Scholar
  26. 26.
    A.M. Dijvestijn, and E.C.M. Hoefsmit. Cell Tiss. Res., in press.Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Elisabeth C. M. Hoefsmit
    • 1
  1. 1.Department of Electron Microscopy, Medical FacultyFree UniversityAmsterdamThe Netherlands

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