Abstract
The afferent lymph supply is essential for the proper functioning of the lymph node. Ablation of the afferent vessels leads to the disappearance of macrophages, interdigitating cells, plasma cells, germinal centres and high endothelial venules (1,2). The majority of T and B lymphocytes enter the node via the blood vessels, but this route is not used by the accessory cells, many of which are derived from precursors in the afferent lymph (3). The lymph contains large cells with actively moving cytoplasmic extensions, or veils. Cells of this type are not found in the efferent or thoracic duct lymph and appear to end their journey in the paracortex, or T-dependent area of the lymph node (4), where they may differentiate into interdigitating cells. Actively phagocytic cells form only 20% of veiled cells and 98% are strongly la-positive (3,5).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
H.R. Hendriks. Academisch Proefschrift, Rodopi, Amsterdam (1981).
H.R. Hendriks, I.L. Eestermans, and E.C.M. Hoefsmit. Cell Tissue Res. 211:375 (1980).
E.C.M. Hoefsmit, E.W.A. Kamperdijk, H.R. Hendriks, R.H.J. Beelen, and B.M. Balfour, in: “The Reticuloendothelial ystem. I Morphology”, I. Carr and W.T. Daems, eds., Plenum Press, New York (1980).
R.H. Kelly, B.M. Balfour, J.A. Armstrong and S. Griffiths. Anat. Rec. 190:5 (1978).
C.J.F. Spry, A.J. Pflug, G. Janossy, and J.H. Humphrey. Clin. Exp. Immunol. 39:750 (1980).
R.M.L. Steinman, L.L. Chen, M.D. Witmer, M.C. Nussenzweig, J.C. Adams, and Z.A. Cohn, in: “Mononuclear Phagocytes II,” R. van Fürth, and Martinus Nijhoff, eds., The Hague (1980).
S.C. Knight, B. Harding, S. Burman, and J. O’Brien, in: “The Molecular Basis of Immune Cell Function”, J.G. Kaplan, ed., Elsevier, North Holland (1979).
J. Farrant, and S.C. Knight. Proc. Natl. Acad. Sci. 76:3507 (1979).
S.C. Knight, B. Harding, S. Burman, and J. Martin. Clin. Exp. Immunol. (1981) in press.
J. O’Brien, S.C. Knight, N.A. Quick, E.H. Moore, and A.S. Platt. J. Immunol. Methods 27:219 (1979).
G. Stingl, S.I. Katz, E.M. Shevach, A.S. Rosenthal and I. Green. J. Invest. Dermatol. 71:59 (1979).
M.C. Nussenzweig, R.M. Steinman, B. Gutchinov, and Z.A. Cohn. J. Exp. Med. 152:1070 (1980).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Plenum Press, New York
About this chapter
Cite this chapter
Balfour, B., O’Brien, J.A., Perera, M., Clarke, J., Sumerska, T., Knight, S.C. (1982). The Effect of Veiled Cells on Lymphocyte Function. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_62
Download citation
DOI: https://doi.org/10.1007/978-1-4684-9066-4_62
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-9068-8
Online ISBN: 978-1-4684-9066-4
eBook Packages: Springer Book Archive