The Immunological Significance of Birbeck Granule Containing Cells

  • E. W. A. Kamperdijk
  • M. v.d. Berg
  • E. C. M. Hoefsmit
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)


Peripheral lymphoid organs such as lymph nodes are composed of functionally different compartments (1): the marginal zone for the induction of the plasma cellular reaction, the germinal centre for the immunological memory (2) and the paracortex for the specific cellular reaction. In each of these areas different types of macrophage demonstrate a particular interaction with lymphocytes, i.e. the marginal zone macrophages, the tingible body macrophages (TBM) in the germinal centre and the interdigitating cells (IDC) in the paracortex (3,4).


Germinal Centre Marginal Zone Transitional Form Popliteal Lymph Node Memory Phase 


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • E. W. A. Kamperdijk
    • 1
  • M. v.d. Berg
    • 1
  • E. C. M. Hoefsmit
    • 1
  1. 1.Department of Electron Microscopy, Medical FacultyFree UniversityAmsterdamThe Netherlands

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