Study of Beta Adrenoceptors on Subpopulations of Thymocytes Separated on Ficoll-Hypaque Density Gradients
In our earlier study we had identified beta adrenoceptors on fetal and newborn thymocytes (1). In view of the fact that thymocyte population in the adult is heterogeneous in terms of stages of maturation and functional competence, this research was undertaken to study the concentration of beta adrenoceptors on the sub-populations of thymocytes separated on discontinuous ficoll-hypaque density gradient (2) in order to examine any correlation between the concentration of these receptors and the immunological competence of various thymocyte subpopulations. In addition, comparison with splenic T lymphocytes, which are more immunoreactive than thymocytes and also differ in terms of adenylcyclase stimulation and levels of cAMP (3,4) have also been made.
KeywordsAdenyl Cyclase Lymphoid Cell Functional Competence Thymic Hormone Nylon Wool
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