Studies on the Maturity of Cells Migrating from the Thymus to the Periphery in Mice

  • Roland Scollay
  • Wei-Feng Chen
  • Graham Mitchell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)


Mature T cells (found in lymph nodes, spleen and thymic medulla) can be distinguished from immature T cells (found in thymic cortex) on the basis of size and pattern of membrane antigen expression (1). The terras “mature” and “immature” are used because cortical thymocytes generally have little or no immune function, while the other populations do.


FACS Analysis Mesenteric Lymph Node Peanut Agglutinin Thoracic Duct Lymph Hydrocortisone Acetate 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Roland Scollay
    • 1
  • Wei-Feng Chen
    • 1
  • Graham Mitchell
    • 1
  1. 1.The Walter and Eliza Hall Institute of Medical ResearchMelbourneAustralia

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