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The Origin of Marginal-Zone Cells

  • D. S. Kumararatne
  • I. C. MacLennan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Abstract

The marginal zone is the outer compartment of the white pulp of mammalian spleens. Most cells found in this area are intermediate-sized lymphocytes (1,2). Surface marker analyses (3–6) have provided strong evidence that these cells are B lymphocytes. Also marginal zone lymphocytes are absent from the spleens of rats treated with heterologous anti-μ antibody from birth (6). In rat spleens marginal-zone B cells outnumber the B lymphocytes found in the follicles by a factor of two to three (6,7).

Keywords

Bone Marrow Cell Thoracic Duct White Pulp Foetal Liver Cell Outer Compartment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • D. S. Kumararatne
    • 1
    • 2
  • I. C. MacLennan
    • 1
    • 2
  1. 1.Department of Bacteriology and ImmunologyThe Western InfirmaryGlasgowUK
  2. 2.Department of ImmunologyBirmingham University Medical SchoolUK

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