Formation of Germinal Centers in the Rat Thymus

  • K. Matsuno
  • S. Ekino
  • M. Kotani
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Abstract

Rats of Wistar strain were given 20 intraperitoneal injections of a saline suspension of typhoid-paratyphoid bacilli (3 × 108) plus serotonin (serotonin Creatinin sulfate 0.25 mg) at 10 day intervals. A large number of thymic germinal centers were formed in females, but not in males. However, orchidectomy induced the formation of germinal centers in the thymus of males as well as females. No thymic germinal centers were formed after injections of either typhoid-paratyphoid bacilli or serotonin only.

Keywords

Creatinin Serotonin Germinal Bacillus Mast 

References

  1. 1.
    K. Matsuno, M. Kotani, S. Ekino, H. Fujii, S. Harada, and Y. Nawa. J. Anat. 129:743 (1979).PubMedGoogle Scholar
  2. 2.
    K. Matsuno, N. Yamanaka, and M. Kotani. Acta Hist. Jap. 44 (1981) in press.Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • K. Matsuno
    • 1
  • S. Ekino
    • 1
  • M. Kotani
    • 1
  1. 1.Department of Anatomy, School of MedicineUniversity of KumamotoKumamotoJapan

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