Lymph Macrophages Enter the Germinal Center of Regional Lymph Nodes
The peripheral lymph contains considerable number of macrophages under normal conditions (1,2). However, the role as well as the fate of macrophages entering the regional lymph node from lymph is not precisely known, nor is localization of macrophages within the node certain. We would like to demonstrate here the migration of lymph macrophages from the peripheral tissues to the germinal center of the regional lymph nodes, suggesting a possible role of macrophages in the transport of antigens from the peripheral tissues to the germinal center.
KeywordsRegional Lymph Node Peripheral Tissue Germinal Center Popliteal Lymph Node Peripheral Lymph
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- 1.J.M. Yoffey, and F.C. Courtice, in: “Lymphatics, Lymph and the Lymphomyeloid Complex”, Academic Press, London (1970).Google Scholar