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Immune Response Regulation

  • Harald von Boehmer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Abstract

During the last years we have learned about cell interactions required to generate effector cells during immune responses. Our knowledge of the cell interactions leading to the production of antibody-forming cells, cells mediating delayed-type hypersensitivity (DTH) reactions and cytotoxic T lymphocytes is advanced because we have been able to study clones of these cell types. Our knowledge of cell interactions leading to generation of T suppressor cells is not quite as detailed; complicated circuits involving three or four discrete steps are invoked by recent experiments. We do not know whether different cell lineages are involved in each step. In the following I would like to concentrate first on aspects concerned with the induction of nonsuppressive effector cells and then discuss some experiments concerned with suppressor cells.

Keywords

Effector Cell Helper Cell Suppressor Cell Soluble Antigen Immune Response Regulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Harald von Boehmer
    • 1
  1. 1.Basel Institute for ImmunologyBasel 5Switzerland

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