Recent Advances in High-Performance Liquid Chromatography of Volatile Natural Products

  • Denis Barron
  • Anni Pabst
Part of the Recent Advances in Phytochemistry book series (RAPT, volume 25)


Gas chromatography (GC) is considered to be the method of choice in the analysis of volatile compounds, because of its high resolving power and the availability of universal detection using flame ionization (FID) detectors. However, GC is mainly an analytical method and its application is limited when preparative isolation of volatile compounds is required. On the other hand, GC analysis of thermolabile and/or polar compounds is often difficult to achieve. Although these problems could be easily solved by the use of liquid chromatography, the latter technique has received limited application in the analysis of volatile constituents because of its poor resolution and the lack of a sensitive universal detector. In the past, the application of liquid chromatography in the analysis of volatiles has been mostly restricted to the prefractionation of crude extracts for GC analysis.


Normal Phase Preparative Isolation Diol Column Aroma Constituent Raspberry Fruit 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Denis Barron
    • 1
  • Anni Pabst
    • 2
  1. 1.Pharmacognosy Laboratory, School of PharmacyJoseph Fourier University-GrenobleLa Tronche CédexFrance
  2. 2.Lehrstuhl für LebensmittelchemieUniversität WürzburgWürzburgGermany

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