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The Effects of 4-Nitroquinoline-N-Oxide (4NQO) at Different Stages of Triturus Limb Regeneration

  • N. P. Zilakos
Part of the NATO ASI Series book series (NSSA, volume 172)

Abstract

The concept that an inverse association may exist between the regenerative capacity of an animal and its susceptibility to neoplasia is old (Waddington, 1935; Prehn, 1971) but even in our days it remains popular (Tsonis, 1987). There is a considerable degree of contradiction in this field since various studies have revealed that some carcinogenic substances do not affect, whereas others have shown that carcinogens arrest regeneration (Tsonis, 1983).

Keywords

Sodium Cacodylate Abnormal Regenerate Carcinogenic Substance Cacodylate Sodium Secondary Regenerate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Iten, L.E., and Bryant, S.V., 1973, Regeneration from differrent levels of amputation in T. viridescens forelimbs. Length, rate and stages, Wilhelm Roux Archiv., 173:263–282.CrossRefGoogle Scholar
  2. Prehn, R.T., 1971, Immunosurveillance, regeneration and oncogenesis, Prog. Exp. Tumor Res., 14:1–24.PubMedGoogle Scholar
  3. Tsonis, P.A., 1983, Effects of carcinogens on regenerating and non-regenerating limbs in Amphibia, Ant. Research, 3:195–202.CrossRefGoogle Scholar
  4. Waddington, C.H., 1935, Cancer and the theory of organisers, Nature, 135:606–608.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • N. P. Zilakos
    • 1
  1. 1.Zoological LaboratoryUniversity of AthensAthensGreece

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