Intercalary Regeneration and Supernumerary Limbs after Proximal or Distal Transposition of the Developing Limb Bud of the Anuran Bufo Bufo in Contralateral Transplantations

  • Panayotis Kostaridis
  • Costas Zafeiratos
Part of the NATO ASI Series book series (NSSA, volume 172)


It is known that developing limbs in Urodeles have the ability for intercalary regeneration. When blastemata of distal origin are grafted proximally without rotation of the transverse axes they interact with the stump so that the deleted skeletal patterns are replaced (Iten and Bryant, 1975; Stocum, 1975). However, when mature hands are grafted to a more proximal level, intercalary regeneration between mature tissues is very poor (Bryant and Iten, 1977, Michael and Hassona, 1982). A similar result is observed in Anurans (Maden, 1981, Michael and Hassona, 1982). Another feature of urodele limb transplantation is the production of supernumerary limbs when distal and proximal tissues are confronted (Iten and Bryant, 1975; Stocum, 1975; Stocum and Melton, 1977; Tank, 1978).


Skeletal Element Bufo Bufo Larval Salamander Ambystoma Mexicanum Intercalary Regeneration 


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Panayotis Kostaridis
    • 1
  • Costas Zafeiratos
    • 1
  1. 1.Zoological LaboratoryUniversity of AthensAthensGreece

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