Neuropeptides Control Regeneration in Planarians
Among existing regulators of regeneration neuropeptides attract particular attention as active modulators of various physiological functions in animals. It seems to be important to systematize the effects of neuropeptides on morphogenesis. Head regeneration of flatworms planarians may serve as a convenient model. The planarians used in the present study belong to the asexual race Ducresia tigrina. Regeneration was estimated using the method of vital computer morphometry based on registration of photocontrast between old (pigmented) and novel (without pigment) body parts of regenerates. Then images of planarians were put into computer memory by digitizer and relative criteria of regeneration were calculated. The criteria were based upon restoration of the initial relations between the lengths of the head and the total body and between the head area and the area of the whole body.