Mechanisms of Transdifferentiation of Pigment Epithelial Cells into Neural Retina: A Hypothesis
The adult amphibian eye is a very convenient model for studying the events involved in the process that has been called transdifferentiation. In this system, which involves regeneration of the lens and/or retina in the adult newt or certain other amphibia, fully differentiated cells of adult somatic tissue are released from the control of the differentiated state and are channeled into a new pathway of cell type differentiation.
KeywordsPigment Epithelium Xenopus Laevis Retinal Pigment Epithelial Cell Growth Area Neural Retina
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