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Mechanisms of Transdifferentiation of Pigment Epithelial Cells into Neural Retina: A Hypothesis

  • Victor Mitashov
Part of the NATO ASI Series book series (NSSA, volume 172)

Abstract

The adult amphibian eye is a very convenient model for studying the events involved in the process that has been called transdifferentiation. In this system, which involves regeneration of the lens and/or retina in the adult newt or certain other amphibia, fully differentiated cells of adult somatic tissue are released from the control of the differentiated state and are channeled into a new pathway of cell type differentiation.

Keywords

Pigment Epithelium Xenopus Laevis Retinal Pigment Epithelial Cell Growth Area Neural Retina 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Stroeva, O.G., and Mitashov, V.I., 1983, Retinal pigment epithelium: Proliferation and differentiation during development and regeneration, Int. Rev. Cytol., 83:221–293.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Victor Mitashov
    • 1
  1. 1.Institute of Developmental BiologyAcademy of Sciences of the USSRMoscowUSSR

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