Rapid Neuronal and Glial Changes in the Phrenic Nucleus Following Spinal Cord Injury: A Possible Morphological Basis for the Unmasking of Functionally Ineffective Synapses

  • Harry G. Goshgarian
  • Jose A. Rafols
Part of the NATO ASI Series book series (NSSA, volume 172)

Summary

The present study describes specific morphological alterations of the normal ultrastructure of the rat phrenic nucleus which occur within four hours after an ipsilateral spinal cord hemisection. Qualitative and quantitative morphometric analyses demonstrated a rearrangement of the glial compartment and synaptic architecture in the phrenic neuropil. It is possible that the injury-induced neuronal and glial changes may be related to the unmasking of a latent motor pathway which restores function to muscle paralyzed by spinal cord injury.

Keywords

Hydrate Agar Citrate Dehydration Paraformaldehyde 

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Harry G. Goshgarian
    • 1
  • Jose A. Rafols
    • 1
  1. 1.Department of Anatomy and Cell BiologyWayne State University School of MedicineDetroitUSA

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