Response of Amputated Xenopus Laevis Forelimbs to Augmentation of the Nerve Supply
This study concerns the effects of nerve augmentation on growth and development of forelimb regenerates in metamorphosed Xenopus laevis froglets. Augmentation was accomplished by implanting spinal ganglia from sibling donors near the base of the host regenerate. The results show that nerve augmentation increases the potential growth of regenerates and also leads to perturbations of the normal cartilaginous outgrowth. However, nerve augmentation does not appear to make a substantial contribution of the definitive pattern formation in the regenerate.
KeywordsSkin Graft Xenopus Laevis Neuronal Cell Body Nerve Supply Spinal Ganglion
Unable to display preview. Download preview PDF.
- Globus, M. and Liversage, R.A., 1975, In vitro studies of limb regeneration in adult Diemictylus viridescens: Neural dependence of blastema cells for growth and differentiation, J. Embrvol. exp. Morph., 33:813–829.Google Scholar
- Goss, R.J., 1983, Chondrogenesis in Regenerating Systems. in: “Cartilage”, vol. 3, Biomedical Aspects. B.K. Hall, ed. Academic Press, New York.Google Scholar
- Konieczna-Marczynska, B. and Skowron-Cendrzak, A., 1958, The effect of the augmented supply on the regeneration in postmetamorphic Xenopus laevis. Folia biol., 6:37–46.Google Scholar
- Simpson, S.B., 1961, Induction of limb regeneration in the lizard, Lycrosoma laterale, by augmentation of the nerve supply, Proc. Soc. Exp. Biol. and Med., 107:108–111.Google Scholar