Effect of Enzymatic Methylation on the Import of in Vitro Synthesized Apocytochrome C into Mitochondria

  • Woon Ki Paik
  • Kwang Sook Park
  • Blaise F. Frost
  • Sangduk Kim
Part of the Advances in Experimental Medicine and Biology book series (NATO ASI F, volume 231)


Little more than a dozen protein posttranslational side-chain modification reactions have been identified. One such reaction, protein methylation, occurs ubiquitously in nature, in organisms ranging from prokaryotic to eukaryotic. The reaction involves N-methylation of lysine, arginine, histidine, alanine, proline and glutamine, O-methylesterifi-cation of glutamic and aspartic acid, and S-methylation of cysteine and methionine (1–3).


Methyl Transferase Rabbit Reticulocyte Lysate Yeast Mitochondrion Protein Methylation Enzymatic Methylation 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Woon Ki Paik
    • 1
  • Kwang Sook Park
    • 1
  • Blaise F. Frost
    • 1
  • Sangduk Kim
    • 1
  1. 1.Fels Research InstituteTemple University School of MedicinePhiladelphiaUSA

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