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Tissue and Capillary Force Changes During the Formation of Intra-Alveolar Edema

  • R. E. Drake
  • A. E. Taylor

Abstract

The Starling forces, capillary pressure (Pc) plasma colloid osmotic pressure (Лc), tissue colloid osmotic pressure (Лt) and tissue fluid pressure (Pt) are related to the volume movement (JV) across any capillary system by the relationship:
$$J_v = K_{FC} \left[ {\left( {P_c - P_t } \right) - \sigma _c \left( {\pi _c - \pi _t } \right)} \right]$$
where KF, C is the filtration coefficient of the capillary bed (ml/min-mm Hg-100 gm) and σ is the Staverman reflection coefficient of the plasma proteins (σ of the protein is equal to 1 if the membrane is impermeable to the protein and is equal to 0 if the protein is as permeable as water in the membrane i.e. velocity of solute/velocity of water = 1). Obviously there is not just one σ but a σ for each of the various protein fractions in the body fluids (α1, α2. and β globulins, albumin and γ globulins); however, for practical purposes we can assume that σ =1 for all plasma proteins and calculate total ΔЛ by the use of the Landis and Pappenheimer equation (1,2).

Keywords

Capillary Pressure Lymph Flow Colloid Osmotic Pressure Total Plasma Protein Plasma Protein Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • R. E. Drake
    • 1
  • A. E. Taylor
    • 1
  1. 1.University of Mississippi Medical CenterJacksonUSA

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