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The Origin of Lipoproteins in the Peritoneal Fluid of the Rabbit: Permeability of the Mesothelium to Macromolecules

  • F. C. Courtice
  • D. C. K. Roberts

Abstract

The perotoneal cavity usually contains a small amount of free fluid. In the present series of experiments the amount present in the normal rabbit was on average about 2ml. When cholesterol was added to the diet for 2 to 3 months to raise the level of plasma cholesterol to 1000 mg/100 ml, the free fluid in the peritoneal civity increased to an average of about 5 ml. This fluid is part of the extracellular fluid of the body throughout which macromolecules are continually moving. The main barrier to this movement resides in the walls of the small blood vessels; the walls of the small lymphatic vessels offer little resistance so that the composition of tissue fluid and lymph is approximately the same (1).

Keywords

Peritoneal Cavity Lymphatic Vessel Peritoneal Fluid Thoracic Duct Free Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • F. C. Courtice
    • 1
  • D. C. K. Roberts
    • 1
  1. 1.John Curtin School of Medical ResearchAustralian National UniversityCanberraAustralia

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