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Structural Aspects of LPS: Role in Evasion of Host Defense Mechanism

  • N. Grossman
  • A. A. Lindberg
  • S. B. Svenson
  • K. A. Joiner
  • L. Leive
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 51)

Abstract

Lipopolysaccharide (LPS) is an important virulence determinant of gram-negative bacteria. It is comprised of three regions: the O-antigenic polysaccharide chain, the R-specific core polysaccharide, and the lipid A region, which exerts, when soluble, all the endotoxic activities of LPS.

Keywords

Membrane Attack Complex Sheep Erythrocyte Polysaccharide Chain Core Oligosaccharide Complement Mediate Lysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Goldman, R.C. and L. Leive. 1980. Eur. J. Biochem. 107: 145–153.PubMedCrossRefGoogle Scholar
  2. 2.
    Palva, T.E., and P.H. Makela. 1980. Eur. J. Biochem. 107:137–144.PubMedCrossRefGoogle Scholar
  3. 3.
    Nurminen, M., Hellerequist, C.G., Valtonen, V.V., and P.H. Makela. 1971. Eur. J. Biochem. 22: 500–505.PubMedCrossRefGoogle Scholar
  4. 4.
    Fuller, N.A., and A.M. Staub. 1968. Eur. J. Biochem. 2: 286–300.CrossRefGoogle Scholar
  5. 5.
    Valtonen M.V., Plosila, M., Valtonen, V.V. and P.H. Makela. 1975. Infec.Immun. 12: 828–835.Google Scholar
  6. 6.
    Valtonen, V.V., 1970. J. Gen. Microbiol. 64: 255–268.PubMedGoogle Scholar
  7. 7.
    Valtonen, V.V., Aird, J., Valtonen, M., Makela, O., and P.H. Makela. 1971. Acta Path. Microbiol. Scand. 79B: 710–715.Google Scholar
  8. 8.
    Valtonen, M.V. and P. Hayry. 1978. Infec. Immun. 19: 26–28.Google Scholar
  9. 9.
    Makela, P.H., Valtonen, V.V., and M.V. Valtonen. 1973. J. Infec. Dis. 128. Suppl.,: S81-S85.CrossRefGoogle Scholar
  10. 10.
    Valtonen M.V., 1977. Infec. Immun. 18: 574–578.Google Scholar
  11. 11.
    Liang-Takasaki, C.-J., Makela, P.H. and L. Leive, 1983., J. Immunol. 128: 1229–1235.Google Scholar
  12. 12.
    Liang-Takasaki, C.-J., Grossman, N., and L. Leive. 1983. J. Immunol. 130: 1867–1870.PubMedGoogle Scholar
  13. 13.
    Grossman, N., and L. Leive. 1984. J. Immunol. 132: 376–385.PubMedGoogle Scholar
  14. 14.
    Svenson, S.B., and A.A. Lindberg. 1977. FEMS Microbiol. Lett. 1: 145–148.CrossRefGoogle Scholar
  15. 15.
    Svenson, S.B., and A.A. Lindberg. 1978. J. Immunol. 120: 1750–1757.PubMedGoogle Scholar
  16. 16.
    Svenson, S.B., and A.A. Lindberg. 1979. J. Immunol. Methods 25: 323–335.PubMedCrossRefGoogle Scholar
  17. 17.
    Robertsson, J.A., Svenson, S.B., and A.A. Lindberg (1982). Infec. Immun. 37: 737–748.Google Scholar
  18. 18.
    Valtonen, V.V. and P.H. Makela. 1971. J. Gen. Microbiol. 69: 107–115.PubMedGoogle Scholar
  19. 19.
    Makela, P.H., Hovi, M., Saxen, H., Valtonen, M., and V. Valtonen. 1988. Immunol. Lett. 19: 217–222.PubMedCrossRefGoogle Scholar
  20. 20.
    Joiner, K.A., 1988. Ann. Rev. Microbiol. 42: 201–230.CrossRefGoogle Scholar
  21. 21.
    Jimenez-Lucho, V.E., Joiner, K.A., Foulds, J., Frank, M.M., and L. Leive. 1987. J. Immunol. 139: 1253–1259.PubMedGoogle Scholar
  22. 22.
    Grossman, N., Joiner, K.A., Frank, M.M., and L. Leive (1986). J. Immunol.136: 2208–2215.PubMedGoogle Scholar
  23. 23.
    Grossman, N., Schmetz, M., Foulds, J., Klima, E.N., Jiminez, V., Leive, L., and K.A. Joiner., 1987. 169: 856–863.Google Scholar
  24. 24.
    Pun, T., Trus, B.L., Grossman, N., Leive, L., and M. Eden. 1985. Electrophoresis 6: 268–273.CrossRefGoogle Scholar
  25. 25.
    Joiner, K.A., Hammer, C.H., Brown, E.J., and M.M. Frank (1982). J. Exp. Med. 155: 797–815.PubMedCrossRefGoogle Scholar
  26. 26.
    Goldman, R.C., Joiner, K.A., and L. Leive. 1984. J. Bacterid. 159: 877–882.Google Scholar
  27. 27.
    Porat, R., Johns, M.A., and W.R. McCabe. 1987. Infec. Immun. 55: 320–328.Google Scholar
  28. 28.
    Joiner, K.A., Grossman, N., Schmetz, M., and L. Leive (1986. J. Immunol. 136: 710–715.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • N. Grossman
    • 1
  • A. A. Lindberg
    • 2
  • S. B. Svenson
    • 3
  • K. A. Joiner
    • 4
  • L. Leive
    • 4
  1. 1.Department of Microbiology, The George S. Wise Faculty of Life SciencesTel Aviv UniversityTel-AvivIsrael
  2. 2.Karolinska InstituteHuddingeSweden
  3. 3.National Biological LaboratoryStockholmSweden
  4. 4.NIHBethesdaUSA

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