Advertisement

Urolithiasis pp 579-588 | Cite as

Characterization of the Calcium Oxalate Crystal Growth Inhibitors in Human Urine

  • E. E. Schrier
  • J. L. Rubin
  • K. E. Lee
  • P. G. Werness
  • L. H. Smith

Abstract

Although the concentration of inhibitors of calcium oxalate crystal growth in stone former’s urine does not appear to differ from that in normal urine1 the inhibitors must be characterized in order to better assess their role in stone disease. We have focused on the development of new methods for their separation and purification, concentrating our efforts on the high molecular weight inhibitors.

Keywords

High Performance Liquid Chromatography High Performance Liquid Chromatography Calcium Oxalate Sodium Oxalate Spontaneous Crystallization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    R. L. Ryall and V. R. Marshall, in: “Proceedings Fourth International Urolithiasis Research Symposium,” L. H. Smith, B. Finlayson, and W. G. Robertson, eds., Plenum Press, New York, (in press).Google Scholar
  2. 2.
    T. Bitter and M. H. Muir, Anal. Biochem. 4:330 (1962).PubMedCrossRefGoogle Scholar
  3. 3.
    R. Almog and T. L. Shirey, Anal. Biochem. 91:130 (1978).PubMedCrossRefGoogle Scholar
  4. 4.
    T. E. Dorsey, P. W. McDonald, and O. A. Roels, Anal. Biochem. 78:156 (1977).PubMedCrossRefGoogle Scholar
  5. 5.
    G. L. Gardner and R. H. Doremus, Invest. Urol. 15:478 (1978).PubMedGoogle Scholar
  6. 6.
    J. L. Meyer and L. H. Smith, Invest. Urol. 13:31 (1975).PubMedGoogle Scholar
  7. 7.
    H. Ito and F. L. Coe, Am. J. Physiol. 233:F455 (1977).PubMedGoogle Scholar
  8. 8.
    A. A. Ansari and R. G. Mage, J. Chromatog. 140:98 (1977).CrossRefGoogle Scholar
  9. 9.
    W. W. Fish, K. G. Mann, and C. Tanford, J. Biol. Chem. 244:4989 (1969).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • E. E. Schrier
    • 1
  • J. L. Rubin
    • 1
  • K. E. Lee
    • 2
  • P. G. Werness
    • 2
  • L. H. Smith
    • 2
  1. 1.Department of ChemistrySUNY at BinghamtonBinghmatonUSA
  2. 2.Mayo ClinicRochesterUSA

Personalised recommendations