The Sources of Phosphocitrate and its Role as an Inhibitor of Calcium Phosphate and Calcium Oxalate Crystallization
Earlier studies reported by Howard1 and Lehninger2 suggested that a substance containing Pi and citrate, and tentatively assigned the structure of phosphocitrate, existed in nature and was a potent inhibitor of hydroxyapatite (HAP) formation. These observations led us to attempt to isolate and characterize phosphocitrate from biological sources with a view to defining a physiological role for this compound in calcification systems.
KeywordsCalcium Oxalate Amorphous Calcium Phosphate Organic Phosphate Calcium Oxalate Crystal Calcium Oxalate Crystallization
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