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Urolithiasis pp 551-556 | Cite as

Rates and Mechanisms of Dissolution of Renal Calculi. III. Mechanisms and Rates of Dissolution of Simulated Oxalate Calculi in Acid and Edta Solutions

  • John Pawelchak
  • Douglas R. Flanagan
  • Anthony P. Simonelli

Abstract

A previous communication1 showed that dissolution or urinary calculi sections did not exhibit zero-order (i. e., constant) rates under sink conditions. Since pure calcium oxalate discs did exhibit a constant dissolution rate, it was concluded that controlling processes other than the intrinsic solution properties of calcium oxalate must be operative in the dissolution behavior of real calculi. In this paper we intend to compare models described previously2 with the dissolution behavior of artificial calculi in various media.

Keywords

Calcium Oxalate EDTA Solution Renal Calculus Dissolution Behavior Sink Condition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    J. Pawelchak, D. R. Flanagan, and A. P. Simonelli, in: “Proceedings of the Fourth International Symposium on Urolithiasis Research,” L. H. Smith, B. Finlayson, and W. G. Robertson, eds. Plenum Press, New York (in press).Google Scholar
  2. 2.
    J. Pawelchak, D. R. Flanagan, and A. P. Simonelli, in: “Proceedings of the Fourth International Symposium on Urolithiasis Research,” L. H. Smith, B. Finlayson, and W. G. Robertson, eds. Plenum Press, New York (in press).Google Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • John Pawelchak
    • 1
  • Douglas R. Flanagan
    • 1
  • Anthony P. Simonelli
    • 1
  1. 1.School of Pharmacy and Institute of Materials ScienceUniversity of ConnecticutStorrsUSA

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