Urolithiasis pp 517-521 | Cite as

Rat Renal Papillary Structure in Oxalate-Induced Microlithiasis, A Scanning Electron Microscope Study

  • S. R. Khan
  • B. Finlayson
  • R. L. Hackett


Most commonly, renal stones are found in the renal calyces or pelvis and several of the hypotheses concerning calculogenesis implicate the papilla as having a central role. Attention was first focused on this region of the kidney by Randall1,2,3, who described minute calculi and calcium plaques on and within renal papilla. Vermeulen et al.4,5 extended these observations in a series of experiments which suggested that the papillary tip was critical in the formation of various types of stones. However, few current studies are available which explore changes in the renal papilla during experimental calculogenesis. To extend further the knowledge of papillary involvement in lithogenesis we examined structural alterations of the papillary surface during calcium oxalate crystalluria.


Calcium Oxalate Renal Stone Scan Electron Microscope Study Calcium Plaque Sodium Oxalate 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • S. R. Khan
    • 1
  • B. Finlayson
    • 1
  • R. L. Hackett
    • 1
  1. 1.College of MedicineUniversity of FloridaGainesvilleUSA

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