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Urolithiasis pp 493-496 | Cite as

Hyperuricosuria in Calcium Oxalate Urolithiasis and its Possible Relationships with Stone Matrix Formation

  • J. G. Brockis
  • R. C. Bowyer

Abstract

The association of calcium oxalate stone formation with hyperuricosuria and hypercalciuria has been the subject of a number of papers1,2,3. It has been known for a considerable time that patients prone to forming recurrent calcium oxalate stones may on occasion form calculi composed of uric acid and the association is clearly more than fortuitous. The explanation for this association has proved quite formidible to resolve, but the importance of this is clear since it has been suggested that lowering urate excretion by the administration of allopurinol may prevent recurrent urinary stone formation2. The studies on this subject are fraught with difficulty because of the time lag needed before any form of therapy for recurrent stone formation can be regarded as successful and in the absence, as yet, of properly performed controlled trials of this drug in stone disease.

Keywords

Stone Formation Calcium Oxalate Urinary Calculus Calcium Oxalate Stone Calcium Urate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • J. G. Brockis
    • 1
  • R. C. Bowyer
    • 1
  1. 1.Royal Perth Hospital and University of Western AustraliaPerthAustralia

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