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Stabilizing Factors for Uric Acid Dihydrate — A Contribution to Uric Acid Stone Formation

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Urolithiasis

Abstract

Recently several authors, by investigations of the topographical phase distribution in uroliths, were able to demonstrate uric acid dihydrate (UAD) in the outer parts of uric acid concrements1 analogous to weddellite in calcium oxalate stones. Scanning electron microscopic studies by our team2,6 also suggest that initially dihydrate is formed, similar to a mechanism suggested for calcium oxalate stone genesis. In the opinion of other authors, one or several urine components can stabilize the metastable UAD phase within a certain pH range3,4. This was an essential starting point for the investigations under discussion.

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References

  1. G. Brien, C. Bick, and G. Schubert, Jenaer Harnsteinsymposium, Wissenschaftliche Beitrage der Friedrich-Schiller-Universitat, Jena S.76 (1977).

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  2. W. Berg, A. Hesse, and H.-J. Schneider, Jenaer Harnsteinsymposium, Wissenschaftliche Beitrage der Friedrich-Schiller-Universitat, Jena S.101 (1977).

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  3. C. J. Laue, G. H. Nancollas, and S. J. Ko, Invest. Urol. 15:473 (1978).

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  4. A. Hesse, H.-J. Schneider, W. Berg, and E. Hienzsch, Invest. Urol. 12:405 (1975).

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  5. J. G. Jediny, Allunionskongreß für Urologie, Kiew S.391 (1978).

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  6. A. Hesse, W. Berg, and C. Bothor, Int. Urol. Nephrology 11:13 (1979).

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Author information

Authors and Affiliations

  1. Clinic of Urology, Friedrich-Schiller-University, Lessingstraße 1, Jena, Germany

    R. H. Börner, H.-J. Schneider & W. Berg

Authors
  1. R. H. Börner
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  2. H.-J. Schneider
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  3. W. Berg
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Editor information

Editors and Affiliations

  1. Mayo Clinic, Rochester, Minnesota, USA

    Lynwood H. Smith

  2. The General Infirmary, Leeds, England

    William G. Robertson

  3. University of Florida, Gainesville, Florida, USA

    Birdwell Finlayson

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© 1981 Springer Science+Business Media New York

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Börner, R.H., Schneider, HJ., Berg, W. (1981). Stabilizing Factors for Uric Acid Dihydrate — A Contribution to Uric Acid Stone Formation. In: Smith, L.H., Robertson, W.G., Finlayson, B. (eds) Urolithiasis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8977-4_78

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  • DOI: https://doi.org/10.1007/978-1-4684-8977-4_78

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8979-8

  • Online ISBN: 978-1-4684-8977-4

  • eBook Packages: Springer Book Archive

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