Urolithiasis pp 459-464 | Cite as

On the Transition Amorphous Calcium Phosphate to Crystalline Octacalcium Phosphate

  • J. M. Garcia Ruiz
  • V. Lopez-Acevedo
  • J. L. Amorós


Most of calcium phosphates in some hard tissues of living organisms belong to the family of apatites. They crystallize in hexagonal or monoclinic systems, and even non crystalline mineral phases have been detected1. Repeated experiments have demonstrated the transformation of amorphous calcium phosphate, ACP, into crystalline calcium phosphate, which is not yet completely understood2–5. There are two different hypotheses to explain this transformation2,3,6. One hypothesis considers ACP dissolution and subsequent transformation into crystalline phosphate as the main mechanism; while the second hypothesis, ACP constitutes an epitaxic substrate for secondary nucleation of the crystalline phase.


Calcium Phosphate Amorphous Calcium Phosphate Tricalcium Phosphate Secondary Nucleation Octacalcium Phosphate 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • J. M. Garcia Ruiz
    • 1
  • V. Lopez-Acevedo
    • 1
  • J. L. Amorós
    • 1
  1. 1.Departamento de Cristalografia y MineralogiaF. C. Geologicas, U. ComplutenseMadridSpain

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