Urolithiasis pp 373-377 | Cite as

Reduction of Urinary Oxalate Excretion in Primary Hyperoxaluria by Diet

  • E. R. Yendt
  • M. Cohanim
  • L. Peters


The medical management of primary hyperoxaluria poses a difficult therapeutic challenge1. The administration of pyridoxine, which facilitates the transamination of glyoxylate to glycine occasionally results in a worthwhile reduction of urine oxalate excretion2–4 but often is without significant effect2,5,6,7. Recently Smith has reported encouraging results with the combined use of pyridoxine and orthophosphates which prevented progression of nephrolithiasis and deterioration of renal function in this disease8.


Sodium Benzoate Oxalate Excretion Primary Hyperoxaluria Urinary Oxalate Excretion Oxalate Content 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • E. R. Yendt
    • 1
    • 2
  • M. Cohanim
    • 1
    • 2
  • L. Peters
    • 1
    • 2
  1. 1.Departments of Medicine and Nutrition ServicesKingston General HospitalKingstonCanada
  2. 2.Department of MedicineQueen’s UniversityKingstonCanada

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