Urolithiasis pp 253-258 | Cite as

Neutral Potassium Phosphate and Thiazide: Combined Treatment in Recurrent Stone Formers

  • A. Scott Klein
  • Donald P. Griffith


Urinary calculous disease accounts for a large number of hospital admissions yearly and calcium oxalate is the most common stone found. Current theories of calculogenesis suggest that stones form as a consequence of two pathologic processes: (1) urinary solute supersaturation and (2) ineffective inhibition as shown by Robertson1.


Calcium Oxalate Stone Episode Thiazide Therapy Calcium Stone Disease Phosphate Therapy 


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  1. 1.
    W. G. Robertson, M. Peacock, R. W. Marshall, D. H. Marshall, and B. E. C. Nordin, N. Engl. J. Med. 294:249 (1976).PubMedCrossRefGoogle Scholar
  2. 2.
    E. R. Yendt, and M. Cohanim, Kid. Int. 13:397 (1978).CrossRefGoogle Scholar
  3. 3.
    W. C. Thomas Jr., Trans. Am. Clin. Climatol. Assoc. 83:113 (1971).Google Scholar
  4. 4.
    M. A. Holliday, R. W. Winters, L. G. Welt, M. McDowell, and J. Oliver, J. Exp. Med. 110:161 (1959).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • A. Scott Klein
    • 1
  • Donald P. Griffith
    • 1
  1. 1.Roy and Lillie Cullen Department of Urologic Research, Department of UrologyBaylor College of MedicineHoustonUSA

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