Short Ammonium Chloride Loading Test for Evaluation of Hyperparathyroidism

  • Peter Alken


The dilemma in the diagnosis of hyperparathyroidism (HPT) is reflected by three factors: Hypercalcemia is still regarded as the most important diagnostic sign, but unless multiple determinations of serum calcium are done, the so-called borderline cases will be missed. Tests that readily identify HPT combine either simple performance, widespread use and low accuracy (CP, TRP, PEI, TMP/GFR)l or sophisticated methods, limited use and high accuracy (PTH, Ca+++, c-AMP). Consequently, some authors perform neck explorations to cure patients with recurrent nephrolithiasis who do not fulfill the diagnostic criteria of HPT. However, the stone recurrence rate may then reach 75%2,3 In this situation, to complete the diagnostic puzzle of hyperparathyroidism additional information is valuable.


Serum Calcium Parathyroid Adenoma Calcium Excretion Neck Exploration Stone Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    U. Binswanger and J. A. Fischer, in: “Klinik der Inneren Sekretion,” A. Labhart, ed., Springer, Berlin, New York, Heidelberg (1979).Google Scholar
  2. 2.
    H. Johansson, L. Thoren, I. Werner, and L. Grimelius, Surgery 77:691 (1975).PubMedGoogle Scholar
  3. 3.
    J. M. P. Siminovitch, R. E. James, C. B. Esselstyn, R. A. Staffron, and L. H. Banowsky, J. Urol. 123:335 (1980).PubMedGoogle Scholar
  4. 4.
    U. Backman, Scand. J. Urol. Nephrol. Suppl. 35 (1976).Google Scholar
  5. 5.
    F. L. Coe, J. J. Firpo, D. L. Hollandsworth, L. Segil, J. M. Canterburry, and E. Reiss, Kid. Int. 8:262 (1975).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Peter Alken
    • 1
  1. 1.Department of UrologyUniversity of MainzWest Germany

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