The Effect of Storage on Serum Oxalate Values
Controversy still exists regarding the true concentration of oxalate in mairanalian blood. Indirect radioisotope methods1–4 have given values of 11.0 — 16.5 μg per 100 ml plasma while chemical- enzymic techniques5–9 have obtained oxalate levels of around 120 μg. More recently, however, Akcay and Rose10 have produced evidence to explain this discrepancy. In the presence of inhibitors of glyoxylate oxidation to oxalate they demonstrated considerably lower levels by their enzymic procedure. Using a modification of the method of Hatch et al.8 we have observed similar serum oxalate levels to Akcay and Rose10 but in the absence of these inhibitors.
KeywordsBoric Acid Enzymic Oxidation Oxalate Concentration True Concentration Meath Hospital
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- 3.A. R. Constable, A. M. Joekes, J. P. Kasidas, P. O’Regan, and G. A. Rose, Clin. Sci. Mol. Med. 56:299 (1979).Google Scholar