Excretion of the CA-Binding Amino Acid, γ-Carboxyglutamate, in Stone-Formers

  • J. Joost
  • S. Silbernagl
  • E. Jarosch


In recent years, there has been increasing interest in a particular Ca-binding amino acid, γ-carboxyglutamate (Gla), with regard to its role in many calcium-dependent physiological processes. This substance appears to be involved in hemostasis, bone calcification and ectopic mineralization. Research concerning the possible role in urinary Ca stone-formation is just beginning.


Uric Acid Fractional Excretion Kidney Stone Uric Acid Stone Renal Handling 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • J. Joost
    • 1
  • S. Silbernagl
    • 1
  • E. Jarosch
    • 1
  1. 1.Departments of Urology, Physiology and PediatricsUniversity of InnsbruckInnsbruckAustria

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