Urolithiasis pp 881-884 | Cite as

Enhancement of Urinary Citrate in Oxalate Stone Formers by the Intake of Alkaline Salts

  • M. Butz
  • H.-J. Dulce

Abstract

Oxalate stone formers have a decreased concentration and excretion of urinary citrate. By oral ingestion of K-Na-citrate (Uralyt-UR) a 100% increase of citrate and a 40% decrease of calcium is achieved. Urinary oxalate, uric acid, magnesium and phosphate remain unaltered under therapy. Two additive effects improving the solubility of calcium oxalate are obtained by the intake of alkaline citrate. Thus it is suggested to extend prophylactic Uralyt-UR therapy to oxalate stone formers.

Keywords

Magnesium Citrate Oxalate Pyrophosphate 

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References

  1. 1.
    B. Kissin, and M. O. Locks, Proc. Soc. Exp. Biol. Med. 46:216 (1941).Google Scholar
  2. 2.
    J. S. Elliot, and B. E. Ribeiro, Invest. Urol. 10:102 (1972).PubMedGoogle Scholar
  3. 3.
    P. O. Schwille, D. Scholz, M. Paulus, W. Engelhardt, and A. Sigel, Invest. Urol. 16:457 (1979).PubMedGoogle Scholar
  4. 4.
    S. G. Welshman, and M. G. McGeown, Br. J. Urol. 48:7 (1976).PubMedCrossRefGoogle Scholar
  5. 5.
    O. Oestberg, Scand. Arch. Physiol. 62:81 (1931).CrossRefGoogle Scholar
  6. 6.
    G. Kohlbecker, and M. Butz, (in press).Google Scholar
  7. 7.
    M. A. Crawford, M. D. Milne, and B. H. Scribner, J. Physiol. 149:413 (1959).PubMedGoogle Scholar
  8. 8.
    D. P. Simpson, Am. J. Physiol. 204:875 (1964).Google Scholar
  9. 9.
    U. S. Barzel, and J. Jowsey, Clin. Sci. 36:517 (1969).PubMedGoogle Scholar
  10. 10.
    P. H. Petritsch, Urol. 10:536 (1977).PubMedCrossRefGoogle Scholar
  11. 11.
    M. Butz, (in preparation)Google Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • M. Butz
    • 1
  • H.-J. Dulce
    • 1
  1. 1.Department of Urology and Department of Clinical Chemistry, Klinikum SteglitzFree University of BerlinBerlinWest Germany

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