Therapeutic Role of Vitamin B6 on Oxalate Metabolism in Urolithiasis and its Effect on Hyperoxaluria Induced in Rats by Ethylene Glycol
Marginal deficiency of vitamin B6 has been shown to promote hyperoxaluria in man1. Even though large doses of pyridoxine may reduce the hyperoxaluria1, the dose of pyridoxine to be administered has not been well defined. Hyperoxaluria in animals can be induced by ethylene glycol or sodium glycolate2. The present study has been undertaken to find out the effect of large doses of pyridoxine on ethylene glycol-induced hyperoxaluria in rats and also in hyperoxaluric stone-forming patients.
KeywordsOxalate Calcium Urinary Oxalate Stock Diet Urinary Oxalate Excretion Calcium Phosphorus
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