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Urolithiasis pp 869-873 | Cite as

Therapeutic Role of Vitamin B6 on Oxalate Metabolism in Urolithiasis and its Effect on Hyperoxaluria Induced in Rats by Ethylene Glycol

  • S. K. Thind
  • R. Nath
  • S. Farooqui
  • M. S. R. Murthy

Abstract

Marginal deficiency of vitamin B6 has been shown to promote hyperoxaluria in man1. Even though large doses of pyridoxine may reduce the hyperoxaluria1, the dose of pyridoxine to be administered has not been well defined. Hyperoxaluria in animals can be induced by ethylene glycol or sodium glycolate2. The present study has been undertaken to find out the effect of large doses of pyridoxine on ethylene glycol-induced hyperoxaluria in rats and also in hyperoxaluric stone-forming patients.

Keywords

Oxalate Calcium Urinary Oxalate Stock Diet Urinary Oxalate Excretion Calcium Phosphorus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    S. N. Gershoff, Vitamins and Hormones 22:581 (1964).PubMedCrossRefGoogle Scholar
  2. 2.
    F. H. C. Chow, D. W. Hamar, and R. H. Udall, Invest. Urol. 12:50 (1974).PubMedGoogle Scholar
  3. 3.
    I. D. P. Wootton, in: “Microanalysis in Medical Biochemistry,” A. Churchill, London (1960).Google Scholar
  4. 4.
    A. Hodgkinson and A. Williams, Clin. Chim. Acta. 36:127 (1972).PubMedCrossRefGoogle Scholar
  5. 5.
    H. Kishi and K. Folkares, J. Nutr. Sci. Vitaminol. 22:225 (1976).PubMedCrossRefGoogle Scholar
  6. 6.
    S. N. Gershoff and S. B. Andrus, Proc. Soc. Exptl. Biol. Med. 109:99 (1962).Google Scholar
  7. 7.
    D. W. Fry and K. E. Richardson, Biochim. Biophys. Acta. 567:482 (1979).PubMedCrossRefGoogle Scholar
  8. 8.
    M. Stanulovic, V. Jeremic, V. Leskovac, and S. Chaykin, Enzyme 21:357 (1976).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • S. K. Thind
    • 1
  • R. Nath
    • 1
  • S. Farooqui
    • 1
  • M. S. R. Murthy
    • 1
  1. 1.Departments of Biochemistry and Experimental MedicinePostgraduate Institute of Medical Education and ResearchChandigarhIndia

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