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Urolithiasis pp 865-868 | Cite as

Alterations in Kidney Enzymes of Oxalate Metabolism in Patients with Urolithiasis

  • S. K. Thind
  • R. Nath
  • G. Verma
  • M. S. Rao
  • B. C. Bapna

Abstract

McCarrison1 described northern India as a “stone-belt”, in which the stones are of a mixture of calcium oxalate and calcium phosphate2. Many etiological factors have been implicated in the formation of idiopathic renal calculi. Recent work on experimental urolithiasis in rats has shown that enzymes of oxalate metabolism are altered in stone formers3. In the present study the role of enzymes involved in urolithiasis in humans has been ascertained by measuring the activities of alkaline phosphatase (AP), lactate dehydrogenase (LDH), glycolate oxidase and glyoxylase I, from biopsy specimens of kidneys collected during operation.

Keywords

Alkaline Phosphatase Lactate Dehydrogenase Stone Formers3 Calcium Oxalate Human Kidney 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • S. K. Thind
    • 1
  • R. Nath
    • 1
  • G. Verma
    • 1
  • M. S. Rao
    • 2
  • B. C. Bapna
    • 2
  1. 1.Department of BiochemistryPostgraduate Institute of Medical Education and ResearchChandigarhIndia
  2. 2.Department of UrologyPostgraduate Institute of Medical Education and ResearchChandigarhIndia

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