Urinary oxalate in man originates from the absorption of dietary oxalate (3–11%) and endogenous synthesis from several precursors1. Ascorbic acid has been reported to provide from 10 to 40% of the total urinary oxalate while glycine provides another 40 Glycolate, glyoxylate, tryptophan, tyrosine, phenylalanine, and serine and possibly citrate, xylitol, hydroxyproline, ethanolamine, and glucose also contribute to oxalate biosynthesis. The pathways of oxalate biosynthesis are summarized in Figure 1.
KeywordsGlycolic Acid Urinary Oxalate Oxalate Excretion Primary Hyperoxaluria Primary Hyperoxaluria Type
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