Urolithiasis pp 807-810 | Cite as

Isolation of the Oxalate Binding Protein

  • Bernardo Pinto
  • José L. Paternain


Intestinal hyperabsorption of oxalate occurs secondary to some intestinal disorders1 but can also be associated with mild hyperoxaluria in the absence of intestinal disease2. Intestinal transport of oxalate appears to be a diffusive mechanism3 dependent on the oxalic acid concentration gradient. This transport appears to be affected by the presence of an oxalate binding protein4 whose physiological significance has not been established. The following paper describes the partial purification of this protein from rabbit small intestine.


Ammonium Sulfate Ammonium Sulfate Precipitate Partial Purification Extract Ammonium Rabbit Small Intestine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    L. H. Smith, A. F. Hofmann, J. T. McCall, and P. J. Thomas, Clin. Res. 18:541 (1970).Google Scholar
  2. 2.
    B. Pinto, G. Crespi, F. Sole-Balcells, and P. Barcelo, Kid. Int. 5:285 (1974).CrossRefGoogle Scholar
  3. 3.
    H. J. Binder, Gastroenterology 67:441 (1974).PubMedGoogle Scholar
  4. 4.
    B. Pinto and J. L. Paternain, Invest. Urol. 15:502 (1978).PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Bernardo Pinto
    • 1
  • José L. Paternain
    • 1
  1. 1.Laboratorio de Exploraciones MetabolicasBarcelonaSpain

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