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The Role of Calcium in the Lethal Hit of T Lymphocyte-Mediated Cytolysis

  • Eric Martz
  • Wendy L. Parker
  • Maurice K. Gately
  • Constantine D. Tsoukas
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 146)

Abstract

The cytolytic T lymphocyte (CTL)1 inflicts lethal damage within minutes after contact with a specific antigen-bearing target cell. The mechanism of this damage remains a mystery. Elsewhere in this volume (1), we have reviewed progress during the past decade towards understanding the mechanism of CTL-mediated killing.

Keywords

Mast Cell Histamine Release Calcium Influx Adhesion Formation Calcium Ionophore A23187 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Eric Martz
    • 1
  • Wendy L. Parker
    • 2
  • Maurice K. Gately
    • 3
  • Constantine D. Tsoukas
    • 4
  1. 1.Department of MicrobiologyUniversity of MassachusettsAmherstUSA
  2. 2.Department of MicrobiologyUniversity of Massachusetts Medical CenterWorcesterUSA
  3. 3.Surgical Neurology Branch, National Institute of Neurological and Communicative Disorders and StrokeNational Institutes of HealthBethesdaUSA
  4. 4.Department of Clinical ResearchScripps Clinic and Research FoundationLa JollaUSA

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