A Search for Target Cell Structures Associated with Susceptibility to NK Cells
Natural killer (NK) cells, regardless of the species from which they are derived, are characterized by their ability to lyse a wide variety of cell types, most notably lymphomas and other tumor cell lines. Normal tissues, including fibroblasts, thymocytes and a portion of bone marrow cells are also lysed, but, in general, normal cells are much less susceptible than tumor cells to NK cell mediated lysis (1,2).
KeywordsNatural Killer Natural Killer Cell Fred Hutchinson Cancer Research L5178Y Cell Natural Killer Cell Population
Unable to display preview. Download preview PDF.
- 3.Durdik, J.M., Beck, B.N., Clark, E.A., and C.S. Henney. “Natural Cell-Mediated Immunity Against Tumors,” Herberman, R.B., Ed., New York. Academic Press, pp. 805–817 (1980).Google Scholar
- 4.Brooks, C.G., Kurlbayashi, K., Sale, G.E., and C.S. Henney. J. Immunol., submitted for publication (1981).Google Scholar