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Renal Excretion of Arginine-Vasopressin in Microalbuminuric Diabetic Patients

  • Giovanni Maria Narelli
  • Mauro Cignarelli
  • Adriano Paternostro
  • Vittoria Romanazzi
  • Giuseppe Passavanti
  • Rosaria Cospite
  • Giovanni De Pergola
  • Pasquale Coratelli
  • Riccardo Giorgino
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 252)

Abstract

Enhanced activity of haemodynamic hormones have been reported to be involved in the development of renal lesions of diabetic kidney1,2. Apart from other pressor factors even plasma arginine-vasopressin (AVP) have been found to be increased in uncontrolled diabetic patients very probably reflecting both a hypovolemic status and an increase in “effective” extracellular fluid osmolality; however, high circulating AVP levels have also been observed in certain well controlled diabetic patients thus suggesting that an alteration of mechanisms regulating AVP secretion exists in diabetes mellitus3,4.

Keywords

Albumin Excretion Rate Urinary Albumin Concentration Microalbuminuric Patient Fluid Osmolality Incipient Nephropathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Giovanni Maria Narelli
    • 1
  • Mauro Cignarelli
    • 1
  • Adriano Paternostro
    • 1
  • Vittoria Romanazzi
    • 1
  • Giuseppe Passavanti
    • 1
    • 2
  • Rosaria Cospite
    • 1
  • Giovanni De Pergola
    • 1
  • Pasquale Coratelli
    • 1
    • 2
  • Riccardo Giorgino
    • 1
  1. 1.Clinica Medica IIIUniversità di Bari PoliclinicoBariItaly
  2. 2.Istituto di NefrologiaUniversità di Bari PoliclinicoBariItaly

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