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Haloformamidines

  • Henri Ulrich

Abstract

Haloformamidines are derivatives of formic acid; the name haloformamidines is used by Chemical Abstracts, which numbers the center carbon atom 1, and lists the nitrogens as N and N’. However, this class of compounds is more closely related to carbamic acid, as evidenced by its synthesis from urea (carbamic acid amide) and cyanamide (carbamic acid nitrile). In a recent article(15) concerned with the synthesis and reactions of substituted chloroformamidine hydrochlorides, the term carbamido chlorides was used. Since chloroformamidine hydrochlorides I are the amido chlorides of carbamide, this generic name is not unreasonable. There is no evidence for the isomeric geminate chloride structure II, and the polar character of I is evidenced by the relatively high melting points of chloroformamidine hydrochlorides, and by their insolubility in nonpolar solvents(15).

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Copyright information

© Plenum Press 1968

Authors and Affiliations

  • Henri Ulrich
    • 1
  1. 1.Donald S. Gilmore Research LaboratoriesThe Upjohn CompanyNorth HavenUSA

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