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The Immunology of Glomerular Nephropathies

  • B. Van Damme
  • V. J. Desmet
Part of the Ettore Majorana International Science Series book series (EMISS, volume 9)

Abstract

Immunological damage is a frequent cause of glomerulonephritis. This can be related to antibodies against glomerular basement membrane antigens or to the deposition or the in situ formation of immune complexes in the glomerulus. Depending on the localisation and the severity of the aggression different degrees of inflammation occur. Adaptation of the mesangium or of the visceral epithelium results in intracapillary proliferation and membranous transformation respectively, while breaks in the glomerular capillary wall result in crescent formation.

Keywords

Immune Complex Glomerular Basement Membrane Crescent Formation Glomerular Damage Membranous Glomerulonephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • B. Van Damme
    • 1
  • V. J. Desmet
    • 1
  1. 1.Laboratorium voor Histochemie en Cytochemie Departement Medische NavorsingKatholieke Universiteit LeuvenLeuvenBelgium

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