The Aortic and Carotid Bodies of Chronically Hypoxic Spontaneously Hypertensive Rats (SHR)

  • J.-O. Habeck
  • C. Huckstorf
  • R. Behm


The carotid bodies represent the most important peripheral arterial chemoreceptors. This is especially true for rats. Bilateral cutting of the carotid sinus nerve or glomectomy leads to severe disturbances in the regulation of breathing in this species (Cardenas and Zapata, 1983; Chiocchio et al., 1984; Hofer, 1986; Martin-Body et al., 1985; Olson et al., 1988). But there is also some evidence for a contribution of other paraganglia than the carotid bodies to respiratory regulation (Sinclair, 1987). Possible candidates are the aortic bodies. Functional experiments did not show any or only a small influence of the thoracic glomic tissue on the regulation of breathing in rats (Cardenas and Zapata, 1983; Martin- Body et al., 1985, 1986; Sapru and Krieger, 1977). Anatomical studies demonstrated different results regarding the presence of aortic bodies in rats of the Wistar and Long-Evans strain (Easton and Howe, 1983; Habeck et al., in press; Mc Donald and Blewett, 1981). The spontaneously hypertensive rats of the OKAMOTO-AOKI strain (SHR), however, represent a strain in which the aortic bodies are regularly detectable and in high numbers (Habeck et al., in press). Therefore, this strain may provide a suitable model for studies about the function of these chemoreceptors in rats.


Recurrent Laryngeal Nerve Carotid Body Chronic Hypoxia Hypobaric Hypoxia Superior Laryngeal Nerve 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • J.-O. Habeck
    • 1
  • C. Huckstorf
    • 2
  • R. Behm
    • 2
  1. 1.Institute of PathologyBezirkskrankenhaus Friedrich WolfKarl-Marx-StadtGDR
  2. 2.Institute of PhysiologyWilhelm-Pieck-UniversityRostockGDR

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