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The Increased Catecholamine Content in the Carotid Bodies of Spontaneously Hypertensive Rats

  • Chapter
Chemoreceptors and Chemoreceptor Reflexes

Summary

The content of noradrenaline and dopamine in the carotid bodies of spontaneously hypertensive rats of Okamoto-Aoki strain was found to be significantly higher than in normotensive Wistar rats. The concentration of dopamine was found to predominate over that of noradrenaline in carotid bodies of normotensive rats, whereas the concentration of these catecholamines was equal in the carotid bodies of spontaneously hypertensive rats. The level of catecholamines in the carotid bodies of renal hypertensive rats did not differ from the control values. The content of serotonin was comparable in all groups of animals. We postulate that the increased level of catecholamines in the carotid bodies of spontaneously hypertensive rats is a biochemical marker of an augmented activity of carotid chemoreceptors in this strain of rats.

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Authors and Affiliations

  1. Depts. of Physiology and Pharmacology, Medical Academy, Krakowskie Przedmieście 26/28, Warsaw, Poland

    J. Przybylski, P. Janicki & A. Trzebski

Authors
  1. J. Przybylski
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  2. P. Janicki
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  3. A. Trzebski
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Systemphysiologie, Dortmund, Federal Republic of Germany

    Helmut Acker

  2. Medical Academy, Warsaw, Poland

    Andrzej Trzebski

  3. University College, Dublin, Ireland

    Ronan G. O’Regan

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© 1990 Plenum Press, New York

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Przybylski, J., Janicki, P., Trzebski, A. (1990). The Increased Catecholamine Content in the Carotid Bodies of Spontaneously Hypertensive Rats. In: Acker, H., Trzebski, A., O’Regan, R.G. (eds) Chemoreceptors and Chemoreceptor Reflexes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8938-5_52

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  • DOI: https://doi.org/10.1007/978-1-4684-8938-5_52

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8940-8

  • Online ISBN: 978-1-4684-8938-5

  • eBook Packages: Springer Book Archive

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