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Autoradiographic Studies on the Effects of Chronic Unilateral Sectioning of a Carotid Sinus Nerve on 5-HT and SP Binding Sites in the Carotid Body and NTS

  • M. R. Dashwood
  • D. S. McQueen
  • M. de Burgh Daly
  • K. M. Spyer
  • Y. Evrard

Abstract

Whilst there is a growing understanding of the neural organization of respiratory (Spyer et al., personal communication) and cardiovascular reflexes (Spyer, 1988), little is knovm concerning the pharmacology of these pathways. Indeed, there is as yet no convincing evidence to specify the transmitters released by the afferents innervating the arterial chemo- receptors and baroreceptors. As the afferents arising from these receptors terminate solely within the nucleus tractus solitarius (NTS), and this nucleus is rich with peptide-containing terminals and perikarya, it has been speculated that there might be some involvement of peptides in these reflexes (Heike et al., 1980).

Keywords

Medulla Oblongata Carotid Body Carotid Bifurcation Carotid Sinus Nucleus Tractus Solitarius 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Carlton, C. G., and Heike, C. J., 1985, Autoradiographic localisation and characterisation of spinal cord substance P binding sites: high densities in sensory, autonomic, phrenic and Onuf’s motor nucleiJ. Neurosci., 5:1653.Google Scholar
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • M. R. Dashwood
    • 1
  • D. S. McQueen
    • 2
  • M. de Burgh Daly
    • 1
  • K. M. Spyer
    • 1
  • Y. Evrard
    • 3
  1. 1.Department of PhysiologyRoyal Free Hospital School of MedicineLondonUK
  2. 2.Department of PharmacologyUniversity of Edinburgh Medical SchoolEdinburghUK
  3. 3.IRISNeuilly sur SeineFrance

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