Autoradiographic Studies on the Effects of Chronic Unilateral Sectioning of a Carotid Sinus Nerve on 5-HT and SP Binding Sites in the Carotid Body and NTS
Whilst there is a growing understanding of the neural organization of respiratory (Spyer et al., personal communication) and cardiovascular reflexes (Spyer, 1988), little is knovm concerning the pharmacology of these pathways. Indeed, there is as yet no convincing evidence to specify the transmitters released by the afferents innervating the arterial chemo- receptors and baroreceptors. As the afferents arising from these receptors terminate solely within the nucleus tractus solitarius (NTS), and this nucleus is rich with peptide-containing terminals and perikarya, it has been speculated that there might be some involvement of peptides in these reflexes (Heike et al., 1980).
KeywordsMedulla Oblongata Carotid Body Carotid Bifurcation Carotid Sinus Nucleus Tractus Solitarius
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