Effect of Deep Peroneal Nerve Stimulation on the Carotid Chemoreceptor Afferent Discharges in Rabbits
Our previous studies (Che Ming-xin and Su Qing-fen, 1988) have shown that deep peroneal nerve (DPN) stimulation may have a modulatory effect on rabbit carotid chemoreceptor pressor response depending on the functional state of the central cardiovascular activity which is related to vagus input, PaCO2, and the depth of anaesthesia. However, the effect of DPN stimulation on the carotid chemoreceptor is less understood. There has been a report (Biscoe and Purves, 1967) showing that passive movement of hind-limb could increase cat carotid chemoreceptor activity. Therefore, it is of interest to examine whether DPN stimulation could enhance carotid chemoreceptor activity (CCA) in the rabbit.
KeywordsMean Arterial Blood Pressure Passive Movement Carotid Body Thin Filament Fiber Preparation
Unable to display preview. Download preview PDF.
- Belmonte, C., and Eyzaguirre, C., 1974, Efferent influences on carotid body chemoreceptors, J. Neurophysiol., 37:1131.Google Scholar
- Biscoe, T. J., and Purves, M. J., 1967, Factors affecting the cat carotid chemoreceptor and cervical sympathetic activity with special reference to passive hind-limb movements, J. Physiol., 190:425.Google Scholar
- Che Ming-xin, and Su Qing-fen, 1988, (in Chinese), Acta Physiol. Sinica, 40:486.Google Scholar
- Eyzaguirre, C., and Lewin, J., 1961, The effect of sympathetic stimulation on carotid nerve activity, J. Physiol., 159:251.Google Scholar
- Eyzaguirre, C., and Zapata, P., 1984, Perspectives in carotid body research, J. Appl. Physiol., 57:931.Google Scholar
- Majcherczyk, St., Coleridge, J. C. G., Coleridge, H. N., Kaufman, N. P., and Baker, D. G., 1980, Carotid sinus nerve efferents: properties and physiological significance. Fed. Proc., 39:2662.Google Scholar
- O’Regan, R. G., 1981, Responses of carotid body chemosensory activity and blood flow to stimulation of sympathetic nerves in the cat, J. Physiol., 315:81.Google Scholar