Effects of Cytochalasin B on the Primary Cultured Capillary Endothelium

  • Koya Honda
  • Masaya Oda
  • Masahiko Nakamura
  • Hirokazu Komatsu
  • Kotaro Kaneko
  • Toshifumi Azuma
  • Yasuhiro Nishizaki
  • Norihito Watanabe
  • Masaharu Tsuchiya
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 242)

Abstract

Actin filaments, one of the cytoskeletal components in non-muscle cells, are known to be involved in cell contractility, implying that they are one of the mediators regulating the microcirculation system. Recently we have reported that endothelial actin filaments are present in the cytoplasm of capillary endothelium both in the gastric mucosa and in primary monolayer culture. The present study is designed to characterize the functional significance of the actin filaments using an in vitro experimental model.

Keywords

Gastric Mucosa Actin Filament Bile Canaliculus Capillary Endothelium Nonmuscle Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Koya Honda
    • 1
  • Masaya Oda
    • 1
  • Masahiko Nakamura
    • 1
  • Hirokazu Komatsu
    • 1
  • Kotaro Kaneko
    • 1
  • Toshifumi Azuma
    • 1
  • Yasuhiro Nishizaki
    • 1
  • Norihito Watanabe
    • 1
  • Masaharu Tsuchiya
    • 1
  1. 1.Department of Internal Medicine, School of MedicineKeio UniversityTokyo 160Japan

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