Alterations in Gastric Mucosal Microvascular Endothelium in a Stressed Condition-Relevance to Gastric Ulcerogenesis

  • Masaya Oda
  • Masahiko Nakamura
  • Koya Honda
  • Hirokazu Komatsu
  • Kotaro Kaneko
  • Toshifumi Azuma
  • Makoto Suematsu
  • Yoshikazu Yonei
  • Norihito Watanabe
  • Masaharu Tsuchiya
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 242)

Abstract

Since the pioneering reports of Bergmann1 and Gushing,2 it has been well known that stress greatly influences gastric functions such as acid secretion, blood flow and peristalsis, and is an important factor in the initiation and recurrence of gastric ulcer. A variety of stresses loaded on human and animal body are transmitted to the stomach via the autonomic nervous system,3 which regulates the secretion, microcirculation and motility of the stomach.

Keywords

Permeability Sludge Serotonin Immobilization Histamine 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Masaya Oda
    • 1
  • Masahiko Nakamura
    • 1
  • Koya Honda
    • 1
  • Hirokazu Komatsu
    • 1
  • Kotaro Kaneko
    • 1
  • Toshifumi Azuma
    • 1
  • Makoto Suematsu
    • 1
  • Yoshikazu Yonei
    • 1
  • Norihito Watanabe
    • 1
  • Masaharu Tsuchiya
    • 1
  1. 1.Department of Internal Medicine, School of MedicineKeio UniversityTokyo 160Japan

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