Abstract
The lysosomal granules’ play an important role in the inflammatory process,2 and a rather detailed picture of their biochemistry, formation and physiology has been drawn.3 The granules are carriers of histamine, heparin and serotonin in eosinophils and basophils and the source of lytic enzymes in neutrophils.4 These granules serve an important function in phagocytosis by contributing to the enzymatic digestion of engulfed microorganisms, and they provide a source of preformed membrane area which may be recruited in certain forms of phagocytosis or during cell spreading on substrates. Although the granules and other cell organelles have been subjected to detailed ultrastructural investigations,5–8 quantitative information on granule membrane area, size, and distribution are limited; quantitative granule studies have been applied only to cells other than the circulating leukocytes.9
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© 1988 Plenum Press, New York
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Schmid-Schönbein, G.W., Chien, S. (1988). Morphometric Studies on Human Leukocyte Granules. In: Chien, S. (eds) Vascular Endothelium in Health and Disease. Advances in Experimental Medicine and Biology, vol 242. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8935-4_12
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DOI: https://doi.org/10.1007/978-1-4684-8935-4_12
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