Peripherally Evoked Spinal Cord Potentials in Neurological Diagnosis

  • D. G. Small


Cerebral responses evoked by peripheral nerve stimulation and recorded from the scalp in man were first investigated by signal averaging over 20 years ago (Dawson 1954). Much has been learned of the normal response and of its alteration in disease but clinical applications have been limited. We have explored the possibility of recording from lower levels of the central sensory pathway and have reported a response which can be recorded over the back of the neck and base of the skull (Matthews, Beauchamp and Small 1974). It appears to be of nervous origin and is likely to be useful in the study of neurological disease, particularly in conditions such as multiple sclerosis where central conduction may be interrupted or delayed.


Multiple Sclerosis Median Nerve Somatosensory Evoke Potential Cortical Response Cervical Myelopathy 
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  1. Dawson, G. D. A summation technique for the detection of small evoked potentials. Electroenceph. clin. Neurophysiol., 1954, 6: 65–84.CrossRefGoogle Scholar
  2. McAlpine, D., Lumsden, C. E., and Acheson, E. D. Multiple Sclerosis: a Reappraisal. 202 pp (Churchill Livingstone, Edinburgh, 1972).Google Scholar
  3. Matthews, W. B., Beauchamp, M. and Small D. G. Cervical somatosensory evoked responses in man. Nature, 1974, 252: 230–232.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • D. G. Small
    • 1
  1. 1.University Department of Clinical NeurologyChurchill HospitalOxfordUK

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